Nessuno dei precedenti ha funzionato per me e stavo risolvendo problemi utilizzando una pagina di supporto ( https://support.microsoft.com/en-us/help/942051/error-message-when-a-user-visits-a-website -that-is-hosted-on-a-server) quindi ho confrontato il file host dell'applicazione con una delle copie di lavoro e sembra che mi mancassero un sacco di gestori e quando li ho aggiunti di nuovo nell'host dell'applicazione ha iniziato a funzionare. Mi mancavano tutti questi
<add name="xamlx-ISAPI-4.0_64bit" path="*.xamlx" verb="GET,HEAD,POST,DEBUG" modules="IsapiModule" scriptProcessor="%windir%\Microsoft.NET\Framework64\v4.0.30319\aspnet_isapi.dll" preCondition="classicMode,runtimeVersionv4.0,bitness64" />
<add name="xamlx-ISAPI-4.0_32bit" path="*.xamlx" verb="GET,HEAD,POST,DEBUG" modules="IsapiModule" scriptProcessor="%windir%\Microsoft.NET\Framework\v4.0.30319\aspnet_isapi.dll" preCondition="classicMode,runtimeVersionv4.0,bitness32" />
<add name="xamlx-Integrated-4.0" path="*.xamlx" verb="GET,HEAD,POST,DEBUG" type="System.Xaml.Hosting.XamlHttpHandlerFactory, System.Xaml.Hosting, Version=4.0.0.0, Culture=neutral, PublicKeyToken=31bf3856ad364e35" preCondition="integratedMode,runtimeVersionv4.0" />
<add name="rules-ISAPI-4.0_64bit" path="*.rules" verb="*" modules="IsapiModule" scriptProcessor="%windir%\Microsoft.NET\Framework64\v4.0.30319\aspnet_isapi.dll" preCondition="classicMode,runtimeVersionv4.0,bitness64" />
<add name="rules-ISAPI-4.0_32bit" path="*.rules" verb="*" modules="IsapiModule" scriptProcessor="%windir%\Microsoft.NET\Framework\v4.0.30319\aspnet_isapi.dll" preCondition="classicMode,runtimeVersionv4.0,bitness32" />
<add name="rules-Integrated-4.0" path="*.rules" verb="*" type="System.ServiceModel.Activation.ServiceHttpHandlerFactory, System.ServiceModel.Activation, Version=4.0.0.0, Culture=neutral, PublicKeyToken=31bf3856ad364e35" preCondition="integratedMode,runtimeVersionv4.0" />
<add name="xoml-ISAPI-4.0_64bit" path="*.xoml" verb="*" modules="IsapiModule" scriptProcessor="%windir%\Microsoft.NET\Framework64\v4.0.30319\aspnet_isapi.dll" preCondition="classicMode,runtimeVersionv4.0,bitness64" />
<add name="xoml-ISAPI-4.0_32bit" path="*.xoml" verb="*" modules="IsapiModule" scriptProcessor="%windir%\Microsoft.NET\Framework\v4.0.30319\aspnet_isapi.dll" preCondition="classicMode,runtimeVersionv4.0,bitness32" />
<add name="xoml-Integrated-4.0" path="*.xoml" verb="*" type="System.ServiceModel.Activation.ServiceHttpHandlerFactory, System.ServiceModel.Activation, Version=4.0.0.0, Culture=neutral, PublicKeyToken=31bf3856ad364e35" preCondition="integratedMode,runtimeVersionv4.0" />
<add name="svc-ISAPI-4.0_64bit" path="*.svc" verb="*" modules="IsapiModule" scriptProcessor="%windir%\Microsoft.NET\Framework64\v4.0.30319\aspnet_isapi.dll" preCondition="classicMode,runtimeVersionv4.0,bitness64" />
<add name="svc-ISAPI-4.0_32bit" path="*.svc" verb="*" modules="IsapiModule" scriptProcessor="%windir%\Microsoft.NET\Framework\v4.0.30319\aspnet_isapi.dll" preCondition="classicMode,runtimeVersionv4.0,bitness32" />
<add name="svc-Integrated-4.0" path="*.svc" verb="*" type="System.ServiceModel.Activation.ServiceHttpHandlerFactory, System.ServiceModel.Activation, Version=4.0.0.0, Culture=neutral, PublicKeyToken=31bf3856ad364e35" preCondition="integratedMode,runtimeVersionv4.0" />
<add name="rules-64-ISAPI-2.0" path="*.rules" verb="*" modules="IsapiModule" scriptProcessor="%windir%\Microsoft.NET\Framework64\v2.0.50727\aspnet_isapi.dll" preCondition="classicMode,runtimeVersionv2.0,bitness64" />
<add name="rules-ISAPI-2.0" path="*.rules" verb="*" modules="IsapiModule" scriptProcessor="%windir%\Microsoft.NET\Framework\v2.0.50727\aspnet_isapi.dll" preCondition="classicMode,runtimeVersionv2.0,bitness32" />
<add name="rules-Integrated" path="*.rules" verb="*" type="System.ServiceModel.Activation.HttpHandler, System.ServiceModel, Version=3.0.0.0, Culture=neutral, PublicKeyToken=b77a5c561934e089" preCondition="integratedMode,runtimeVersionv2.0" />
<add name="xoml-64-ISAPI-2.0" path="*.xoml" verb="*" modules="IsapiModule" scriptProcessor="%windir%\Microsoft.NET\Framework64\v2.0.50727\aspnet_isapi.dll" preCondition="classicMode,runtimeVersionv2.0,bitness64" />
<add name="xoml-ISAPI-2.0" path="*.xoml" verb="*" modules="IsapiModule" scriptProcessor="%windir%\Microsoft.NET\Framework\v2.0.50727\aspnet_isapi.dll" preCondition="classicMode,runtimeVersionv2.0,bitness32" />
<add name="xoml-Integrated" path="*.xoml" verb="*" type="System.ServiceModel.Activation.HttpHandler, System.ServiceModel, Version=3.0.0.0, Culture=neutral, PublicKeyToken=b77a5c561934e089" preCondition="integratedMode,runtimeVersionv2.0" />
<add name="svc-ISAPI-2.0-64" path="*.svc" verb="*" modules="IsapiModule" scriptProcessor="%windir%\Microsoft.NET\Framework64\v2.0.50727\aspnet_isapi.dll" preCondition="classicMode,runtimeVersionv2.0,bitness64" />
<add name="svc-ISAPI-2.0" path="*.svc" verb="*" modules="IsapiModule" scriptProcessor="%windir%\Microsoft.NET\Framework\v2.0.50727\aspnet_isapi.dll" preCondition="classicMode,runtimeVersionv2.0,bitness32" />
<add name="svc-Integrated" path="*.svc" verb="*" type="System.ServiceModel.Activation.HttpHandler, System.ServiceModel, Version=3.0.0.0, Culture=neutral, PublicKeyToken=b77a5c561934e089" preCondition="integratedMode,runtimeVersionv2.0" />